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WHERE ARE WE GETTING OUR TOXIC EXPOSURES?

2010/03/26
Published

What is a toxin?

Toxins are products that are potentially harmful to the body. They come from our environment and from our bodies as a natural byproduct of all the metabolic processes of the body. For example, the liver performs over 40,000 metabolic processes, and therefore excretion of toxins is essential for good . If a byproduct of our metabolism begins to accumulate in our system, then it can become a toxin. A classic example is estrogen for women. When a woman does not recycle and excrete her estrogens efficiently, they accumulate in the body and irritate key estrogen receptor sites in the body, principally the breast and uterine tissue, pre-disposing her to the development of estrogen based cancers. Add the challenge of efficient estrogen metabolism to modern society’s use of the birth control pill (synthetic hormones) and the use of synthetic hormones for menopause treatment and you drastically increase a woman’s risk for developing cancer. It is no wonder therefore, that our breast cancer rates have not fallen as the issue of methylation of estrogen is not being addressed!

The purpose of this article is to give the reader an introduction to understanding the nature of our exposure and to give you information to help you start to reduce your toxic exposure now! Future articles will go into great depth regarding specific toxins and conditions associated with toxic exposure.

When does a toxin begin to harm us?

When most of us think of toxic exposure we think of being poisoned by something. We imagine that we should feel an immediate effect, like some type of overdose from exposure. However, environmental toxins are more subtle and slow acting. The damage they cause depends upon the cumulative effect of the toxins over time, where the body stores the toxin, how the toxin interacts with our metabolism, how inefficient or burdened our detoxification pathways are based upon our genetic makeup, the state of our immune health, the state of our digestive system (our barrier to the outside world), our additional toxic lifestyle, the added effect of other toxins backing up our system, the interaction of toxins together and the type of damage the toxin causes over time.

Because our environmental toxic exposure is cumulative, industry is slow to make changes favoring profits over health in this country. Because environmental exposure is cumulative, its effects are not immediate and thus industries and government choose to debate over whether something actually causes a disease rather than choosing to eliminate the chemical because it does not promote health! In the mean time we slowly accumulate ever increasing amounts of toxins and wonder why each generation becomes sicker, with more obesity and inflammatory diseases than the prior generation. The American Medical Association published a statement last year stating that this generation was the first in which we will begin to see parents outliving their young! We as a society need to be greatly alarmed by that. We need to choose health over complacency and not waste time over debate.

Where are these toxins?

We get them from our mother in the womb, from breast milk, from our food, our medications and supplements (dye used to color the pills, preservatives, fillers) our cosmetics, the air we breathe outdoors and indoors and from the clothing we wear. The following environmental “toxins” have been shown “conclusively” to affect the development of the nervous system and contribute to autism, attention deficit disorder (ADD/ADHD), dyslexia, OCD, Asburger’s syndrome, brain fog, visual processing disorders, auditory processing disorders, insomnia, chronic fatigue, fibromyalgia, and aggravate all immune disorders such as Chron’s disease, irritable bowel, arthritis, Hashimoto’s thyroiditis, acid reflux, eczema, seasonal allergies, food sensitivities, food allergies, and environmental chemical sensitivities.

The most preventable toxin affecting behavioral and learning disabilities is that of alcohol during pregnancy. Fetal Alcohol Syndrome (FAS) is considered part of the Fetal Alcohol Spectrum Disorder (FASD). Even low consumption of alcohol during pregnancy can have permanent effects upon a child’s cognitive performance.

Nicotine and environmental tobacco smoke (ETS), and second hand smoke has shown to affect behavior disorders and developmental delays in children and young adults. Cigarette smoke contains over 3500 toxins alone, not to mention the addictive effect to the smoker of nicotine. Some of these toxins are mycotoxins, toxins from fungi used to fuel the addictive cravings.

Pesticides come from agriculture and our own backyards to an estimated 1 billion pounds into our yards a year in the United States alone! Exposure to organophosphates in yards and school playgrounds, parks and such enhance the risk for developmental disorders that include issues with memory and motor performance. Remember the effect is cumulative. Depending upon the genetic make up of the child and their toxic levels, some children will suffer more than others.

Pesticides in our food are a huge problem that is not discussed as openly as it could in the media. A few years ago a local newspaper took samples of common grocery food items (non-organic) and was shocked to find the levels of toxic pesticides exceed FDA guidelines. They published a top ten list of foods not to eat unless they were organic as a result. Potatoes and strawberries hit the top ten list. What should have happened is that these “toxic” foods should have been taken off the shelves and the industry challenged to make drastic changes to protect us from these contaminants. Local news media that could have spread the word to protect the public failed to act. Again, economics over health.

Smog, car exhaust, all polycyclic aromatic hydrocarbons (PAHs) are know mutagens and carcinogens. They are generated by our cars, trucks and buses, present also in tobacco smoke and coal-fired power plants. For a fetus, it can affect birth weight where the mother to live in a smoggy town and increase the baby’s risk for cognitive and developmental delays.

Solvents from the workplace used for industrial cleaning, janitorial cleaning, from alcohol, turpentine, acetone, tetrachloroethylene and toluene are know to also induce low birth weight and cause developmental delays. More than 50 million metric tons of solvents are used in the United States with declared exposures to over 10 million individuals in the workplace alone!

Arsenic is found to be the first toxin excreted with patients undergoing heavy metal chelation and that is often their discovery that they were high in arsenic! It is one the first metals the body purges before releasing more toxic metals such as lead and mercury. Arsenic is found as a common contaminant in drinking water, and accumulates faster from diets high in shrimp. Arsenic has known neurological effects in the development of children and the slow poisoning of adults.

Polychlorinated biphenyls (PCBs) are chlorinated compounds used in electrical transforms, the insulation fluids, cooling fluids and other electrical compounds in industry. PCB exposure is cumulative and is known to affect motor skills, learning and memory.

Flame retardants, polybrominated diphenyl ethers (PBDEs) are mandatorily used in fabrics for children’s clothing and in all cloth furniture, such as your couch, and bed mattress. Constant contact results in our body absorbing these products which are known to be neurotoxins affecting motor activity and cognitive performance. It’s the best of two evils, either one’s clothing catches fire easily or you take your chances over time in accumulating toxic neurodegenerative chemicals.

Both PCBs and PBDEs, dioxins, flame retardants, organochloride pesticides, DDT, heavy metals, phthalates and perfluorinated compounds (PFCs) disrupt hormonal function in both men and women. Some of these products are legally allowed as food-can liners! Childhood endocrine imbalances from childhood obesity, to early onset of menses in girls to high estrogens in boys accounts for the estrogenic effects of these chemicals.

Mercury from cement plant fumes to amalgam fillings to thimerisol in vaccines is a known potent neurotoxin. Coal plants and coal-burning electric utilities spew mercury vapors in the air.

Fluoride added to drinking water to reduce dental decay has a backlash effect upon those susceptible. It is also found in toothpaste and mouthwashes. Those suffering from hypothyroid conditions, autoimmune thyroid such as Hashimoto’s thyroiditis, Wilson’s disorder are vulnerable. Published studies also show that children’s IQ decreased in areas where fluoride was used in the drinking water. Emerging research also suggests accelerated calcification to the pineal gland in adults contributing to a host of hormonal imbalances.

Lead, still present in the paints at many schools in our country and old homes continues to accumulate in our blood stream. Lead combines with bioavailable calcium in our body to form the plaques that lead to atherosclerosis and arteriosclerosis. Cardiovascular disease is a leading cause of death in modern society and lead toxicity stimulates arteriole plaque formation and storage of lead in our bones. Lead from car exhaust is a principal source of environmental exposure.

EDTA is the best known chelator for lead and its removal from the body is one of the slowest, taking years. Therefore, taking minute amounts of EDTA in the form of a gum that even children can chew is helpful in preventing the storage of this toxic metal in the body. The EDTA gum can be purchased online at www.immunematrix.com (EZ Defense Gum – 100 count SKU: SKU16167) and helps to reduce the daily accumulation of lead. Another way of helping to removed lead is EDTA bath salts, safe for children and adults and is a fabulous way to detoxify the skin, over time lightening hyper-pigmentation and clarifying the skin. (Beyond Clean – 567 grams SKU: SKU16161)

Food additives from food colorings, food preservatives, food flavor enhancers, food thickeners, and stabilizers all add toxic stress to our systems. Additives such as colorings, tartrazine, sodium benzoates, msg all are neurotoxins. Some individuals are more sensitive to minute exposures than others. Symptoms can range from headache, chronic migraine, ADD, ADHD, impulsive behaviors, sudden changes in mood or attention, brain fog, chronic fatigue, food allergy symptoms, irritable bowel, nose bleeds, chronic sinus congestion, to cognitive disorders in both children and adults. All children suffering from developmental disorders, cognitive impairment, autism etc. must eliminate food additives from their diet.

In all the descriptions of toxins mentioned above, the toxin was studied alone for its effect upon the body, again as if it were a poison. However, we are exposed to minute amounts of all the toxins listed above and more daily! No one has studied the cumulative effect of mixing all these toxins in a body and increasing their doses over time aside from the emerging correlation that chronic inflammatory diseases, auto-immune diseases and degenerative diseases all have a toxic element to them. The body breaks down over time in its ability to eliminate these toxins and the cascade of immune triggers begins. Future articles will address the interaction of toxicity to specific disorders, but suffice it to say here that increasing toxic load increases your risk for developing a chronic inflammatory condition, an auto-immune condition, and affects your body’s ability to ward of infection allowing it to become chronic in your body. It is also a major reason why we have such an explosion of autism, ADD, ADHD, chronic fatigue, fibromyalgia, eczema, asthma, and a host of inflammatory driven conditions such as arteriosclerosis, arthritis, irritable bowel, and migraine.

What can you do now to minimize your cumulative toxic exposure?

1)      Eat clean fresh produce, preferably organic. If you are unable to purchase all organic foods, choose organic potatoes, and strawberries, apples and vegetables whose skin you eat.

2)      Use a fruit and vegetable wash designed to eliminate pesticide residue from the surface of produce purchased.

3)      Eliminate any food that requires a preservative. Shop the perimeter of your grocery store only, as the aisles are filled with foods packaged in cans and boxes, full of preservatives. Keep it fresh only.

4)      Eliminate aluminum from your deodorants; use natural crystal deodorants.

5)      Eliminate sodium laural sulfate from your toothpaste, and all products containing fluoride from toothpaste and mouthwash.

6)      Use natural organic cosmetics.

7)      Use natural enzyme based, and green products to clean your home.

8)      Change pesticide usage to natural products. Many pest control companies now will used if asked essential oils to ant and bug proof the perimeter of the home.

9)      Use natural laundry cleaner and dryer sheets.

10)  Eliminate sodas and can drinks from your diet

11)  Stop smoking…anything

12)  Stop or reduce your consumption of alcohol

13)  Stop habitual use of over the counter medications and seek answers to why you are dependent upon them

14)  Become aware of your toxic exposure from your hobbies: stain glass, pottery, paints, photography, gardening etc.

15)  Use face masks to reduce exposure when painting and doing remodel or home repairs and use gloves around solvents when needed.

Future articles will go into more detail the manner in which we need to detoxify specific toxins and how their presence contributes to our chronic health issues. Taking the above mentioned steps will be a significant improvement in what you can do now to reduce the cumulative effects of environmental toxic exposure and help your body to begin to clear the years of accumulated residue hindering your body’s ability to heal.

Please note:
Information on this site is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional. You should not use the information on this site for diagnosing or treating a health problem or disease, or prescribing any medication or other treatment.

NON-SECRETORS, CHRONIC FATIGUE, AND TOXICITY

2010/03/19
Published

Toxins are anything the body needs to excrete. They can be the natural byproducts of digestion, as well as the byproducts of drugs ingested, over the counter medications taken, hormones, herbs and homeopathics, to contaminants we ingest with our food, we breathe in through pollution, through the “off gassing” of carpets, paints, upholstery fabrics, dry cleaning of clothing, perfumes, and that which we absorb through our skin in our cosmetics, lotions, soaps and oral care products. Today more than ever, our bodies are surrounded by unprecedented degrees of foreign substances that our bodies must learn to excrete both in number and volume.

If you take the food and environmental element of pollution and add the increased number of vaccinations now given to our youth, which were completely unheard of one generation ago, you have a significant increase in heavy metal exposure from the vaccines to our youth at birth! Therefore, our livers and immune systems often are assaulted before they are developed sufficiently to be able to handle this extra burden of toxin elimination.

Toxic accumulation plays a significant role in:

1)      increasing immune sensitivities to food, grass, weeds, pollens, chemical sensitivities

2)      increase free radical damage to the body, increasing carcinogenic cell replication

3)      increase erosion of cell wall membranes which impact cellular nutrient absorption and defenses against pathogens like opportunistic dysbiotic gut bacteria, yeast, candida, protozoal, parasitic and viral attack

4)      erode cell wall membranes especially in nerve tissue and neurons in the brain

5)      inhibit cellular genetic repair

6)      inhibit endocrine/hormone function

7)      increase the attraction and retention of bacteria, yeast and candida in the body

8)      interfere with nerve conduction, affecting hearing, focus, attention, mental processing, and motor neuron function contributing to weakness of limbs etc.

9)      the development of “sticky blood”, increased agglutination of red blood cells increasing one’s stroke risk

Not everyone is capable genetically of clearing toxins from the body at the same rate and efficiency. There have been different marker developed in the last two to five years to touch upon different aspects of a person’s ability to detoxify. One marker, the brainchild of Dr. Peter D’Adamo has been found to have profound impact on the patients seen by Immune Matrix. It is called a Secretor Test. It is a saliva test kit that can be done at home and sent in to the lab. It take approximately three weeks to find out if one is considered a Secretor or Non-Secretor.

The Secretor test is a genetic test to determine if your red blood cells “secrete” your ABO blood-type antigens in your body secretions. According to Dr. D’Adamo’s recent research, a majority of the world are secretors with a minority of approximately 15% non-secretors. The non-secretors are the most challenged to in taking on and eliminating toxins from the body from any source. Therefore, if you suffer from any chronic condition and especially if it is immune or inflammation driven, as in autism, ADD, ADHD, OCD, Asburger’s, chronic fatigue, fibromyalgia, environmental chemical sensitivites, latex allergies, arthritis, irritable bowel, acid reflux or any chronic digestive disorder, then it is essential to find out if you are a non-secretor. Once you know, it is like knowing your blood type, it will not change.

Immune Matrix has every patient take this test so that it can determine from the outset which patients have to be treated with “kid gloves” per se, in red flagging those that need additional assistance and dosing adjustments to detoxify and to take on therapeutic programs to eliminate pathogens from the body. The rate you clear toxins, determines the rate at which you can repair your cell walls and the rate at which you can excrete heavy metals and kill off and eliminate pathogens from the body.

Immune Matrix specializes in seeing patients referred to them by doctors who hit a wall in the treatment of their patients because of their increased reactivity to what they are given, and because they are unable to stay on a drug, herb or supplement without feeling worse or becoming reactive to it. If you find yourself challenged to take a prescribed drug, herb, homeopathic, tincture or supplement, take it as a huge sign that your body’s rate of detoxification and elimination cannot keep up with the dosages given to you as part of your therapy. In many cases, patients cannot stay with a prescribed course of treatment until they have cleared their intra and extracellular matrix and repaired cell wall membranes sufficiently to be able to then take on the additional burden of die-off and metabolic processing of drugs, herbs and the like. Immune Matrix tells its patients in an easy to understand manner that this is like trying to redecorate the house when you have not removed the old haggard wallpaper. The body’s ability to excrete toxins, the level of toxic accumulation, the type of toxic accumulation all need to be factored in AND monitored while any patient undergoes any course of treatment.

If you find that you are a non-secretor, then you need to pace yourself in terms of the number of prescribed medications, herbs, supplements you take so as not to overwhelm your body’s ability to excrete. And you need to focus on helping your body excrete toxins with adequate methylation support and drainage. More will be discuss in future articles on this complex topic.

Tests can be ordered by clicking on Pharmashare image on the right side bar and then click on Books and test tab to place  order. 

It is also highly recommended that you find a practitioner that can run a BIA test on you periodically to obtain quantitative metabolic data on your cell wall membranes, intra and extra cellular toxic load among other key metabolic information. This way you will be able to determine if the therapeutic process is breaking you down faster than your body is able to repair!

Emerging research is also beginning to correlate an association between certain disease susceptibilities to blood type and blood/secretor status. Research on the blood types shows grouping variations in levels of stomach acid, in the types of immune responses to certain foods, and glutens and even reactions to and preferances to specific species of probiotics and proteins necessary for health. Our red blood cell plays a bigger part in our metabolism than previously realized.

Immune Matrix has found in its routine testing that those individuals that test non-secretors AND are blood type A, tend to have the most significant challenges and sensitivities to excreting toxins. Their digestive systems become symptomatic when stressed metabolically and ultimately prevent the patient from successfully finishing a course of prescribed treatment. If you are blood type A and non-secretor, you need careful monitoring and assistance with detoxification on a cellular level to prevent overwhelming your system and causing more harm and inflammatory reactions. Therefore, being armed with knowledge will help you help yourself in pacing the type of therapeutic program you enter and in monitoring your progress. It is therefore essential for non-secretor Blood type A’s to determine their Genotype status with a Licensed  Genotype/Blood type Practitioner.

Please note:
Information on this site is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional. You should not use the information on this site for diagnosing or treating a health problem or disease, or prescribing any medication or other treatment.

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KEY ELEMENTS IN CHRONIC FATIGUE:

2010/02/27
Published

In the 10+ years that Anna Manayan has been treating chronically ill patients certain common factors come into play that affect the syndrome called Chronic Fatigue. She is currently treating chronically ill patients at her clinic Immune Matrix which located in Milpitas California Please check her clinic’s website at http://www.immunematrix.com . This is a summary of my interview with her. 

DETOXIFICATION PATHWAYS:

One does not have to have elevated liver enzymes to have a compromised detoxification pathways. Many patients have gone to their doctors, had blood tests run and were told their liver enzyme were fine, but these same patients knew that every time the tried to take a chelator to excrete heavy metals from their body, or take antibiotics, chlorella, or even a homeopathic or herbal detoxifier they felt even sicker. Why is that?

Both Western and Integrative medicine agree that the more compromised the liver’s ability to break down and bind circulating toxins (food metabolities, pathogen metabolities, drug metabolities, metals, pesticides, herbicides, petrochemicals from our air and food and water) the more compromised the immune system becomes. You don’t need to have elevated liver enzymes to have compromised liver detoxification pathways. The key involves the function of the immune system.

The more chronically ill a patient, the more likely their immune system has developed a “recognition” to a key detoxification metabolite. Most learned patients are aware that there are genetic defects called SNPS that increase their activation when the body is in a higher state of inflammation but one does not need to have genetic SNPS alone to have compromises in their ability to detoxify. A classic example of a detox pathway issue involves the immune system recognizing methionine, a simple amino acid! This prevents the patient from taking in methyl donors from their supplements like DMG, TMG, NAC, etc.. But the problem is usually more extensive than just having an immune recognition for methionine, and it involves the metabolites from methionine and the methylation pathway and other key detoxification pathways that also involve glutathione.

This sounds rather complicated but it is largely reversible when it involves immune recognition of a metabolite. Immune Matrix has developed an extensive database to test patients for the minute details involving their detoxification pathways. As a result, patients who cannot chelate, cannot take supplements, cannot take sulfur donors, methyl donors, cysteine donors, L-tryptophan, GABA precursors, and the like are able to get treated and begin the excrete toxins that their body has locked within their tissues.

How does a patient know if their detox pathways are functioning better? Immune Matrix uses urine and fecal labs and BioImpedence testing to determine the type and level of excretion of toxins and to determine whether the toxins are locked “within” the cells, “between” cells or locked in fat cells. Advanced computerized testing also gives us generalized information as to the nature of the toxic burden, be it food metabolities, heavy metals, pesticides or dead pathogens the body as not yet eliminated.

How long does it take for a patient to determine if their detoxification pathways are compromised? A 30 minute computerized exam is sufficient in most cases to determine the extent and nature of the toxic burden affecting a patient.

Why is it important to know if my detoxification pathways are working uninhibited by my immune system? In order for the body to continue process antibiotics, herbal and homeopathic remedies, it has to be able to eliminate them efficiently. If you can improve your ability to detoxify, and Immune Matrix specializes in taking on cases sent by other practitioners where the patient can’t take anything anymore without reacting, and thus flunks out of the doctor’s treatment protocol, then a patient can return to their treatment modality with regained vigor. 

CHRONIC INFECTION:

How does chronic infection play a part in chronic fatigue? We at Immune Matrix have consistently seen the presence of long standing viral and bacterial infections such as Epstein Barr, Rocky Mt. Spotted Fever, HHV-6, cytomeg.virus, strep. and even lyme co-infectants and lyme disease pathogens to name the most common big hitters.

Are these pathogens regularly tested by doctors? No because in most part western medicine feels that there is nothing that can be done to eradicate them from the body. In some cases a patient is put on an anti-viral medication to suppress it, but we have found that this inhibits the body in its ability to excrete the pathogen and reduce its viral load. Even in the case of strep found living in the digestive tract, most doctors do nothing as this strep is anti-biotic resistant.

How do these pathogens contribute to chronic fatigue? Generally speaking stress weakens the immune system and allows the pathogen to gain a foothold in the body. Over time the immune system weakens to identifying the presence of the pathogen, like princess sitting on the pea, over time it stops noticing the irritation. Patients will go through cycles of feeling better but not their old self and then feeling weak and tired again. This is because the pathogen gains a foothold and the body begins a compromised fight that does not completely eradicate the pathogen but only keeps it under check. Over time this round robin cycle fatigues the immune system and also weakens the adrenal glands causing adrenal fatigue and exhaustion. Once the adrenal glands become exhausted, the don’t repair themselves easily or overnight and never when a pathogen continues to co-exist to the extent that it causes chronic fatigue.

How do I know if I have one of these pathogens? Blood tests are available with many labs to screen for common chronic fatigue viral pathogens. However, we at Immune Matrix do a computerized screening to help determine what blood tests are needed to save patients the cost of expensive labs and from missing a commonly overlooked pathogen. We see this time and time again!

Does Immune Matrix have a method to eliminate chronic fatigue pathogens? Yes we do. We have a proprietary array of serial dilution homeopathics and herbal blended tinctures that have proved over time in label tests to be effective in eradicating these pathogens. We also have a treatment protocol to rebuild adrenal strength as the pathogens are eliminated.

Please note:
Information on this site is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional. You should not use the information on this site for diagnosing or treating a health problem or disease, or prescribing any medication or other treatment.

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